Disintegration Test Apparatus
Description of Disintegration Test Apparatus:
Disintegration apparatus for solid dosage forms ( Tablets, capsules etc) and Disintegration apparatus for semisolid dosage forms ( Suppositories and pessaries ) The USP device to test for disintegration time consists of six glass tubes each of three inches length, open at the top, and held against a 10 mesh screen at the bottom end of the basket rack assembly. To test for the disintegration time, a single tablet is placed in each tube, and the basket rack is positioned in a 1-L beaker containing water or simulated gastric fluid, or stimulated intestinal fluid.
The temperature of the system is maintained at 37+/-2oc and the tablets remain 2.5 cm below the surface of the liquid on their upward movement and descend not closer than 2.5 cm from the bottom of the beaker.A standard motor-driven device is used to move the basket assembly containing the tablets up and down through a distance of 5 to 6 cm at a frequency of 28 to 32 cycles per minute. Perforated plastic discs may also be used in the test.
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